gene 1,263 words KG: IFFO1
Contents

IFFO1 — Intermediate Filament Family Orphan 1

🧬 Gene Info
Gene SymbolIFFO1
Full NameIntermediate Filament Family Orphan 1
Chromosome6p21.1
Protein TypeGene
Functionis a human gene encoding a protein belonging to the intermediate filament family[@snyman1995].
Primary Expressionvarious tissues, including the brain, where it localizes primarily to the nuclear envelope
Subcellular Localization- **Nuclear envelope**: Primary localization
Molecular Weight50 kDa
Amino Acids462 aa
Exons12
GeneCardsIFFO1
Human Protein AtlasIFFO1
Coiled-coil motifsMediate dimerization and assembly
Lamin-binding sitesEnable interaction with nuclear lamina
Phosphorylation sitesRegulate assembly/disassembly
Associated DiseasesAlzheimer's disease, Parkinson's disease
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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