KCNK3

Understanding Entity Pages

This page aggregates everything SciDEX knows about KCNK3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Potassium two-pore domain channel gene KCNK3 (TASK-1)

View on Wiki →

graph TD
    KCNK3["<b>KCNK3</b>"]
    pulmonary_arterial_hypertension{"pulmonary arterial hypertension"}
    KCNK3 -->|"associated with"| pulmonary_arterial_hypertension
    BMP_signaling(["BMP signaling"])
    KCNK3 -->|"regulates"| BMP_signaling
    pulmonary_vascular_smooth_muscle_cell["pulmonary vascular smooth muscle cell"]
    KCNK3 -->|"expressed in"| pulmonary_vascular_smooth_muscle_cell
    KCNK3 -->|"causes"| pulmonary_arterial_hypertension
    proliferation["proliferation"]
    KCNK3 -->|"inhibits"| proliferation
    PUM1["PUM1"]
    KCNK3 -->|"regulates"| PUM1
    apoptosis["apoptosis"]
    KCNK3 -->|"inhibits"| apoptosis
    KCNK5["KCNK5"]
    KCNK3 -->|"associated with"| KCNK5
    Hypertension{"Hypertension"}
    KCNK3 -->|"activates"| Hypertension
    Heart_Failure{"Heart Failure"}
    KCNK3 -->|"activates"| Heart_Failure
    Als{"Als"}
    KCNK3 -->|"activates"| Als
    ALS{"ALS"}
    KCNK3 -->|"activates"| ALS
    PUM1 -->|"downregulates"| KCNK3
    KCNK2["KCNK2"]
    KCNK2 -->|"regulates"| KCNK3
    KCNK1["KCNK1"]
    KCNK1 -->|"regulates"| KCNK3
    PAH["PAH"]
    PAH -->|"regulates"| KCNK3
    KCNK6["KCNK6"]
    KCNK6 -->|"regulates"| KCNK3
    AND["AND"]
    AND -->|"regulates"| KCNK3
    style KCNK3 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0