PAH

Understanding Entity Pages

This page aggregates everything SciDEX knows about PAH: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

PAH is a gene implicated in neurodegeneration research. Key relationships include: associated with, activates, regulates. Associated with ALS, Aging, Als. Connected to 139 entities in the SciDEX knowledge graph.

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graph TD
    PAH["PAH"]
    PAH -->|"target for"| Cardiovascular["Cardiovascular"]
    PAH -->|"activates"| Als["Als"]
    PAH -->|"target for"| Ms["Ms"]
    PAH -->|"activates"| Heart_Failure["Heart Failure"]
    PAH -->|"expressed in"| Fibrosis["Fibrosis"]
    PAH -->|"target for"| Cancer["Cancer"]
    PAH -->|"expressed in"| Hypertension["Hypertension"]
    PAH -->|"expressed in"| Inflammation["Inflammation"]
    PAH -->|"target for"| Tumor["Tumor"]
    VASCULAR_REMODELING["VASCULAR_REMODELING"] -->|"causes"| PAH
    KCNK2["KCNK2"] -->|"regulates"| PAH
    KCNK1["KCNK1"] -->|"regulates"| PAH
    KCNK3["KCNK3"] -->|"regulates"| PAH
    KCNK6["KCNK6"] -->|"regulates"| PAH
    PI3K["PI3K"] -->|"target for"| PAH
    OVERVIEW["OVERVIEW"] -->|"target for"| PAH
    LDLR["LDLR"] -->|"activates"| PAH
    INFLAMMATION["INFLAMMATION"] -->|"regulates"| PAH