Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about KIF5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| AMYLOID-BETA | binds | protein | 0.90 |
| GE/GI | interacts_with | protein | 0.80 |
| STAU1 | interacts_with | protein | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m | 0.348 | neurodegeneration | Mitochondrial transfer between astrocyte |
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| KIF5A de novo mutation associated with myoclonic seizures and neonatal onset pro [PMID:27414745] | Rydzanicz M, Jagła M, Kosinska J, Tomasi | Clin Genet | 2017 | 1 |
| TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and [PMID:23395375] | van Spronsen M, Mikhaylova M, Lipka J, S | Neuron | 2013 | 1 |
| Delineation of the TRAK binding regions of the kinesin-1 motor proteins. [PMID:24161670] | Randall TS, Moores C, Stephenson FA | FEBS Lett | 2013 | 1 |
| Therapeutic developments in pancreatic cancer. [PMID:37798442] | ["Hu Z", "O'Reilly E"] | Nature reviews. Gastroenterolo | 2024 | 0 |
| Defining treatment-resistant depression. [PMID:31638723] | ["Gaynes B", "Lux L", "Gartlehner G", "A | Depression and anxiety | 2020 | 0 |
| Emerging trends in global freshwater availability. [PMID:29769728] | ["Rodell M", "Famiglietti J", "Wiese D", | Nature | 2018 | 0 |
| Acute Heart Failure: Definition, Classification and Epidemiology. [PMID:28785969] | ["Kurmani S", "Squire I"] | Current heart failure reports | 2017 | 0 |
| Invasive ductal carcinoma: relationship between pathological characteristics and [PMID:28658335] | ["Aquino R", "Vasques P", "Cavalcante D" | Revista do Colegio Brasileiro | 2017 | 0 |
| The Impact of Intergenerational Cultural Dissonance on Alcohol Use Among Vietnam [PMID:26598062] | ["Kane J", "Johnson R", "Robinson C", "J | The Journal of adolescent heal | 2016 | 0 |
| A proliferative burst during preadolescence establishes the final cardiomyocyte [PMID:24813607] | ["Naqvi N", "Li M", "Calvert J", "Tejada | Cell | 2014 | 0 |
| Human plasma glycome in attention-deficit hyperactivity disorder and autism spec [PMID:20974899] | ["Pivac N", "Knezevi\u0107 A", "Gornik O | Molecular & cellular proteomic | 2011 | 0 |
| The Crumbs complex: from epithelial-cell polarity to retinal degeneration. [PMID:19625503] | ["Bulgakova N", "Knust E"] | Journal of cell science | 2009 | 0 |
| CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell [PMID:18971423] | ["Landsman L", "Bar-On L", "Zernecke A", | Blood | 2009 | 0 |
| GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins [PMID:15644324] | Brickley K, Smith MJ, Beck M, Stephenson | The Journal of biological chem | 2005 | 0 |