gene 503 words KG: KIF5B 2026-03-21
kind:genesection:genesstate:published
Contents

KIF5B Gene

🧬 Gene Info
Gene SymbolKIF5B
FunctionThe KIF5B gene encodes Kinesin-1 Heavy Chain Protein, a protein involved in various cellular processes relevant to neuronal function and survival.
Primary Expressionvarious brain regions, with notable expression in: - Cerebral cortex - Hippocampus - Basal gang
PathwaysIGF-1
Ensembl IDENSG00000153257
GeneCardsKIF5B
Human Protein AtlasKIF5B
Associated DiseasesALS, neurodegeneration
InteractionsOPTN, MYC, OPTINEURIN, PVALB, SST, AURKB
KG Connections118 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (7)

Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.48
Axonal RNA Transport Reconstitution
Score: 0.45
Mitochondrial RNA Granule Rescue Pathway
Score: 0.40
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (7)

Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

See Also (15)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: activates
Packard Center for ALS Research
institution · KG edge: activates
KIF15 Gene - Kinesin Family Member 15
gene · KG edge: associated_with
GAP43 Gene
gene · KG edge: associated_with
cdkn2a
gene · KG edge: interacts_with

Knowledge Graph (12 edges)

KIF5B regulates CD38
KIF5B regulates MIRO1
KIF5B interacts_with OPTN
KIF5B interacts_with MYC
KIF5B activates OPTN
KIF5B activates OPTINEURIN
KIF5B associated_with CDC42
KIF5B interacts_with PVALB
KIF5B interacts_with SST
KIF5B associated_with GAP43