protein 827 words KG: KIF5APROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

KIF5A Protein

🔬 Protein Info
Gene SymbolKIF5A
Chromosome12q13.3
Protein FamilyKinesin-1 family (KHC)
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary ExpressionNeurons (CNS and PNS), particularly in axons
Subcellular LocalizationAxon, dendrites, neuronal soma
Molecular Weight103 kDa
Amino Acids350 aa
PathwaysCargo Transport, Intracellular Transport, autophagic flux, lysosomal axonal transport, ubiquitin-proteasome
UniProt IDP33175
NCBI Gene ID3790
Ensembl IDENSG00000130224
OMIM176602
GeneCardsKIF5A
Human Protein AtlasKIF5A
Associated DiseasesAls, Alzheimer's disease, Amyotrophic Lateral Sclerosis, Ms, Spastic Paraplegia Type 10, disease
Known Drugs/CompoundsTMT
InteractionsKIF5C, Kinesin, KIF5B, NEK1, TBK1, NEUROTOXICITY
KG Connections79 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph