Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about L-TYPE CALCIUM CHANNEL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | L-TYPE CALCIUM CHANNEL |
| Aliases | VGCCs |
| Molecular Weight | 248.6 kDa |
| Amino Acids | 373 aa |
| Exons | 47 |
| Pathways | Neurodegeneration |
| Interactions | NMDA |
| KG Connections | 4 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
flowchart TD
L_TYPE_CALCIUM_CHANNEL(["L-TYPE CALCIUM CHANNEL"])
Neurodegeneration("Neurodegeneration")
NMDA(["NMDA"])
ANGIOGENESIS("ANGIOGENESIS")
Astrocytes["Astrocytes"]
Astrocyte["Astrocyte"]
microglia["microglia"]
L_TYPE_CALCIUM_CHANNEL -->|"involved in"| Neurodegeneration
L_TYPE_CALCIUM_CHANNEL -.->|"inhibits"| NMDA
L_TYPE_CALCIUM_CHANNEL -->|"activates"| ANGIOGENESIS
L_TYPE_CALCIUM_CHANNEL -->|"activates"| Astrocytes
L_TYPE_CALCIUM_CHANNEL -->|"activates"| Astrocyte
microglia -->|"activates"| L_TYPE_CALCIUM_CHANNEL
style L_TYPE_CALCIUM_CHANNEL fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff| Target | Relation | Type | Str |
|---|---|---|---|
| NMDA | inhibits | protein | 0.50 |
| Astrocytes | activates | cell_type | 0.50 |
| Astrocyte | activates | cell_type | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| microglia | activates | cell_type | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning L-TYPE CALCIUM CHANNEL in their description or question text
No additional research found