Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about LAMP3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | LAMP3 |
| Full Name | Lysosomal Associated Membrane Protein 3 |
| Chromosome | 3q27.2. |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | mature dendritic cells and plays critical roles in: - MHC class II antigen presentation: Colocalizes with MHC class II compartments - Immune syn |
| Molecular Weight | 61.7 kDa |
| UniProt ID | [Q9UQ15](https://www.uniprot.org/uniprot/Q9UQ15) |
| Ensembl ID | ENSG00000046651 |
| GeneCards | LAMP3 |
| Human Protein Atlas | LAMP3 |
| Associated Diseases | neurodegeneration |
| KG Connections | 9 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["LAMP3"]
N1["Als"]
N0 -->|"expressed in"| N1
N2["ABCG1"]
N0 -->|"expressed in"| N2
N3["WTAP"]
N0 -->|"expressed in"| N3
N4["RORA"]
N0 -->|"expressed in"| N4
N5["TGM2"]
N0 -->|"expressed in"| N5
N6["PIK3R1"]
N0 -->|"expressed in"| N6
N7["NR1D2"]
N7 -->|"expressed in"| N0
N8["CKAP4"]
N8 -->|"expressed in"| N0
N9["GAIN"]
N9 -->|"expressed in"| N0
N10["neurodegeneration"]
N0 -->|"implicated in"| N10
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classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
class N1 disease
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class N3 gene
class N4 gene
class N5 gene
class N6 gene
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class N9 geneHypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||