protein 787 words KG: LAMP3 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

LAMP3 Protein

🔬 Protein Info
Gene SymbolLAMP3
Full NameLysosomal Associated Membrane Protein 3
Chromosome3q27.2.
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionmature dendritic cells and plays critical roles in: - MHC class II antigen presentation: Colocalizes with MHC class II compartments - Immune syn
Subcellular Localization</strong></td><td>Lysosomes, Late Endosomes, Cell Surface (dendritic cells)</td></tr>
Molecular Weight61.7 kDa
UniProt ID[Q9UQ15](https://www.uniprot.org/uniprot/Q9UQ15)
Ensembl IDENSG00000046651
GeneCardsLAMP3
Human Protein AtlasLAMP3
Associated Diseasesneurodegeneration
KG Connections9 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (4)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Lysosomal Positioning Dynamics Modulation
Score: 0.43
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35

Related Analyses (6)

Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed

See Also (9)

Packard Center for ALS Research
institution · KG edge: expressed_in
TGM2 — Transglutaminase 2
gene · KG edge: expressed_in
RORA — RAR Related Orphan Receptor A
gene · KG edge: expressed_in
PIK3R1 Gene
gene · KG edge: expressed_in
NR1D2 (Nuclear Receptor Subfamily 1 Group D Member 2)
gene · KG edge: expressed_in

Knowledge Graph (9 edges)

LAMP3 expressed_in ABCG1
LAMP3 expressed_in RORA
LAMP3 expressed_in TGM2
LAMP3 expressed_in PIK3R1
LAMP3 expressed_in WTAP
LAMP3 expressed_in Als
NR1D2 expressed_in LAMP3
CKAP4 expressed_in LAMP3
GAIN expressed_in LAMP3