entity

LIPID_PEROXIDATION

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about LIPID_PEROXIDATION: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

12Connections
1Hypotheses
0Analyses
3Outgoing
6Incoming

Wiki Pages (21)

Knowledge base pages for this entity

Canonical Page

Lipid Peroxidation in Neurodegeneration

mechanism · 3848 words

cbs-psp-daily-action-plan

therapeutic · 30834 words

Progressive Supranuclear Palsy (PSP)

disease · 12907 words

Corticobasal Syndrome (CBS)

disease · 11374 words

Novel Therapy Index

idea · 10647 words

Alpha-Synuclein Pathology

mechanism · 6288 words

Outgoing (4)

TargetRelationTypeStr
FERROPTOSIScausesphenotype0.87
FERROPTOSISregulatesphenotype0.72
FERROPTOSISactivatesphenotype0.72

Incoming (8)

SourceRelationTypeStr
ACSL4activatesgene0.72
LPCAT3activatesgene0.72
ALOXactivatesgene0.72
ROScausesphenotype0.72
FERROPTOSISregulatesphenotype0.64

Targeting Hypotheses (1)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
Senescence-Induced Lipid Peroxidation Spreading 0.533 neurodegeneration Senolytic therapy for age-related neurod

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (18)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
Klebsiella pneumoniae Induces Ferroptosis and Lactation Dysfunction in Bovine Ma [PMID:40937759] Mao P, Wang Z, Duan J, Dong P, Yuan C, L J Agric Food Chem 2025 1
Targeting ferroptosis: novel therapeutic approaches and intervention strategies [PMID:41425591] Luo Y, Long M, Wu X, Zeng L Front Immunol 2025 1
Trimetazidine attenuates Ischemia/Reperfusion-Induced myocardial ferroptosis by [PMID:39134283] Tan M, Yin Y, Chen W, Zhang J, Jin Y, Zh Biochem Pharmacol 2024 1
Discovery of a glycosylated colchicine derivative as a neuroprotective agent for [PMID:41455281] ["Jash M", "Gupta S", "Garg S", "Khan J" European journal of medicinal 2026 0
The NADPH oxidase inhibitor Vas2870 prevents myocyte ferroptosis and improves ca [PMID:41671579] Wang J, Li CM, Yang B, Tantai RN, Guo HX British journal of pharmacolog 2026 0
From association to mechanism: Prenatal PFAS Co-exposures induces fetal neural t [PMID:41485332] Chen Y, Cheng Q, Yang C, Li S, Lin H, Li Journal of hazardous materials 2026 0
Silencing myeloid cell leukemia-1 improves apoptotic and ferroptotic responses i [PMID:41540498] Fang F, Xu Q, Shen S, Wang S, Bao C European journal of medical re 2026 0
Traditional Chinese Herbal Formula XuMingZhuSan Alleviates Neuronal Ferroptosis [PMID:41822239] Liu X, Wang C, Han L, Xiao Y, Yu H, Hu Z Food science & nutrition 2026 0
Psoraleae Fructus combined with Walnut kernels improves postmenopausal osteoporo [PMID:41016294] ["Hu L", "Luo M", "Zhu X", "Wang Z", "Ya Phytomedicine : international 2025 0
Polystyrene microplastics induced spermatogenesis disorder via disrupting mitoch [PMID:39577614] ["Jin H", "Xue B", "Chen X", "Ma T", "Ma Environmental pollution (Barki 2025 0
Yi-Nao-Jie-Yu Prescription Relieves Post-Stroke Depression by Mitigating Ferropt [PMID:40214929] ["Zhang Y", "Tang Q", "Yao J", "Liu H", Journal of neuroimmune pharmac 2025 0
Light-triggered carbon monoxide-induced activation of enhanced ferritinophagy-me [PMID:41080723] ["Liu Q", "Zhang J", "Yu L", "Chen Y", " Materials today. Bio 2025 0
Triptolide induces hepatotoxicity by promoting ferroptosis through Nrf2 degradat [PMID:39503881] ["Guo L", "Yang Y", "Ma J", "Xiao M", "C Cell biology and toxicology 2024 0
Mifepristone protects acetaminophen induced liver injury through NRF2/GSH/GST me [PMID:38906233] ["Shi Y", "Xu N", "Liu B", "Ma Y", "Fu X Free radical biology & medicin 2024 0
Use of Deep-Learning Assisted Assessment of Cardiac Parameters in Zebrafish to D [PMID:37679058] ["Liu C", "Wang Y", "Zeng Y", "Kang Z", Advanced science (Weinheim, Ba 2023 0
In Vivo Assessment of Ferroptosis and Ferroptotic Stress in Mice. [PMID:35384401] ["Ide K", "Souma T"] Current protocols 2022 0
En masse DNA Electroporation for in vivo Transcriptional Assay in Ascidian Embry [PMID:34692910] Darras S Bio-protocol 2021 0
Management of primary aldosteronism and mineralocorticoid receptor-associated hy [PMID:32424201] ["Morimoto S", "Ichihara A"] Hypertension research : offici 2020 0