disease

microcephaly

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about microcephaly: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

12Connections
0Hypotheses
0Analyses
5Outgoing
3Incoming

No summary available yet. View on Wiki →

Disease Info
Associated GenesEPILEPSY
KG Connections8 knowledge graph edges
DatabasesOMIMOrphanetClinicalTrialsPubMed

Wiki Pages (20)

Knowledge base pages for this entity

NPM1 Gene

gene · 5653 words

CNTN4 — Contactin 4

gene · 4497 words

Epigenetic Dysregulation in Neurodegeneration

mechanism · 4376 words

Neuronal Ceroid Lipofuscinosis (NCL)

disease · 4122 words

KARS1

gene · 4073 words

Pathway Diagram

flowchart TD
    microcephaly["microcephaly"]
    GRAY_MATTER("GRAY MATTER")
    OCLN(["OCLN"])
    VAMP3(["VAMP3"])
    Genes["Genes"]
    SGMS1("SGMS1")
    Cognitive_Impairment("Cognitive Impairment")
    EPILEPSY(["EPILEPSY"])

    microcephaly -->|"associated with"| GRAY_MATTER
    microcephaly -->|"associated with"| OCLN
    microcephaly -->|"associated with"| VAMP3
    microcephaly -->|"associated with"| Genes
    microcephaly -->|"associated with"| SGMS1
    microcephaly -.->|"inhibits"| Cognitive_Impairment
    EPILEPSY -->|"associated with"| microcephaly
    EPILEPSY -.->|"inhibits"| microcephaly

    style microcephaly fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff

Outgoing (6)

TargetRelationTypeStr
OCLNassociated_withgene0.50
VAMP3associated_withgene0.50
SGMS1associated_withconcept0.50
GRAY MATTERassociated_withconcept0.50
Cognitive Impairmentinhibitsphenotype0.50

Incoming (6)

SourceRelationTypeStr
WDR91 deficiencycausesphenotype0.90
EPILEPSYassociated_withgene0.50
EPILEPSYinhibitsgene0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found