Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about microcephaly: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Associated Genes | EPILEPSY |
| KG Connections | 8 knowledge graph edges |
| Databases | OMIMOrphanetClinicalTrialsPubMed |
Knowledge base pages for this entity
flowchart TD
microcephaly["microcephaly"]
GRAY_MATTER("GRAY MATTER")
OCLN(["OCLN"])
VAMP3(["VAMP3"])
Genes["Genes"]
SGMS1("SGMS1")
Cognitive_Impairment("Cognitive Impairment")
EPILEPSY(["EPILEPSY"])
microcephaly -->|"associated with"| GRAY_MATTER
microcephaly -->|"associated with"| OCLN
microcephaly -->|"associated with"| VAMP3
microcephaly -->|"associated with"| Genes
microcephaly -->|"associated with"| SGMS1
microcephaly -.->|"inhibits"| Cognitive_Impairment
EPILEPSY -->|"associated with"| microcephaly
EPILEPSY -.->|"inhibits"| microcephaly
style microcephaly fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff| Target | Relation | Type | Str |
|---|---|---|---|
| OCLN | associated_with | gene | 0.50 |
| VAMP3 | associated_with | gene | 0.50 |
| SGMS1 | associated_with | concept | 0.50 |
| GRAY MATTER | associated_with | concept | 0.50 |
| Cognitive Impairment | inhibits | phenotype | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| WDR91 deficiency | causes | phenotype | 0.90 |
| EPILEPSY | associated_with | gene | 0.50 |
| EPILEPSY | inhibits | gene | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||