Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NFAT1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | NFAT1 |
| Full Name | NFAT1 |
| Protein Type | Gene |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 120 kDa |
| Pathways | calcium signaling |
| NCBI Gene ID | Search NCBI |
| GeneCards | NFAT1 |
| Human Protein Atlas | NFAT1 |
| Associated Diseases | neurodegeneration |
| Interactions | NFAT2, PP2B, APP, BACE1 |
| KG Connections | 6 knowledge graph edges |
| Databases | GeneCardsUniProtHPASTRING |
Knowledge base pages for this entity
graph TD
NFAT1(["NFAT1"])
style NFAT1 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff
NFAT2(["NFAT2"])
PP2B(["PP2B"])
calcium_signaling(["calcium signaling"])
T_cells(["T cells"])
neurodegeneration["neurodegeneration"]
NFAT1 -->|"activates"| NFAT2
NFAT1 -->|"activates"| PP2B
NFAT1 -->|"participates_in"| calcium_signaling
NFAT1 -->|"expressed_in"| T_cells
NFAT1 -->|"implicated_in"| neurodegeneration
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
classDef drug fill:#1a2a2a,stroke:#80cbc4,color:#e0e0e0
class NFAT2 protein
class PP2B protein
class calcium_signaling protein
class T_cells protein
class neurodegeneration disease| Target | Relation | Type | Str |
|---|---|---|---|
| NFAT2 | activates | gene | 0.55 |
| calcium signaling | participates_in | pathway | 0.55 |
| PP2B | activates | gene | 0.55 |
| T cells | expressed_in | cell_type | 0.55 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||