Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Neurovascular Coupling: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| cerebral perfusion | regulates | process | 0.90 |
| Blood-Brain Barrier Dysfunction | associated_with | process | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| 28515434 | ensures rapid increase in | paper | 0.90 |
| 28515434 | regulates | paper | 0.90 |
| 28515434 | is a mechanism for | paper | 0.90 |
| TRPV4 | contributes_to | gene | 0.90 |
| KCNJ2 | regulates | gene | 0.85 |
| PIEZO1 | contributes_to | gene | 0.85 |
| Kir2.1 | regulates | protein | 0.85 |
| TRPA1 | contributes_to | protein | 0.80 |
| time-restricted feeding | associated_with | process | 0.80 |
| mitochondrial fragmentation | associated_with | process | 0.80 |
| Blood-Brain Barrier | associated_with | process | 0.80 |
| CD2AP | involved_in | gene | 0.75 |
| HBOT | restores | drug | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Cerebral VSMC foam cells induce pericyte detachment via PDGF | 0.473 | neurodegeneration | How does P2RY12-mediated VSMC dysfunctio |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-25 | 12 hypotheses Top: 0.640
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
Hypotheses and analyses mentioning Neurovascular Coupling in their description or question text
No additional research found