CD2AP

Understanding Entity Pages

This page aggregates everything SciDEX knows about CD2AP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

CD2AP is a protein involved in neurodegeneration research. Key relationships include: co discussed, associated with, implicated in. Associated with AD, ALI, ALS. Connected to 70 entities in the SciDEX knowledge graph.

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graph TD
    CD2AP["<b>CD2AP</b>"]
    Cerebrovascular_Dysfunction["Cerebrovascular Dysfunction"]
    CD2AP -->|"causes"| Cerebrovascular_Dysfunction
    Endothelial_Cells["Endothelial Cells"]
    CD2AP -->|"expressed in"| Endothelial_Cells
    Cerebrovascular_Function(["Cerebrovascular Function"])
    CD2AP -->|"involved in"| Cerebrovascular_Function
    Blood_Brain_Barrier_Function(["Blood-Brain Barrier Function"])
    CD2AP -->|"regulates"| Blood_Brain_Barrier_Function
    Alzheimer_s_disease{"Alzheimer's disease"}
    CD2AP -->|"associated with"| Alzheimer_s_disease
    p38_MAPK["p38 MAPK"]
    CD2AP -->|"regulates"| p38_MAPK
    neuron["neuron"]
    CD2AP -->|"expressed in"| neuron
    tau_pathology(["tau pathology"])
    CD2AP -->|"regulates"| tau_pathology
    Alzheimer{"Alzheimer"}
    CD2AP -->|"associated with"| Alzheimer
    Ms{"Ms"}
    CD2AP -->|"associated with"| Ms
    Als{"Als"}
    CD2AP -->|"inhibits"| Als
    ALS{"ALS"}
    CD2AP -->|"inhibits"| ALS
    REST["REST"]
    REST -->|"activates"| CD2AP
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"]
    ALZHEIMER_S_DISEASE -->|"inhibits"| CD2AP
    NEURON["NEURON"]
    NEURON -->|"inhibits"| CD2AP
    REELIN["REELIN"]
    REELIN -->|"activates"| CD2AP
    ALZHEIMER["ALZHEIMER"]
    ALZHEIMER -->|"associated with"| CD2AP
    ALZHEIMER -->|"co discussed"| CD2AP
    ALZHEIMER_S["ALZHEIMER'S"]
    ALZHEIMER_S -->|"co discussed"| CD2AP
    APOE["APOE"]
    APOE -->|"co discussed"| CD2AP
    style CD2AP fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0