Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about O-GlcNAc: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| De Novo Nucleotide Synthesis | regulates | pathway | 0.95 |
| NAD Production | regulates | process | 0.90 |
| Glucose Metabolism | involved_in | pathway | 0.85 |
| Glutamine Metabolism | involved_in | pathway | 0.85 |
| phosphate | modulates | process | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| O-GlcNAcylation at T212 competes with phosphorylation to red | 0.380 | alzheimers-disease-and-related-tauopathies | How can ESCRT or SNARE targeting achieve |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-15 | 2 hypotheses Top: 0.636
neurodegeneration | 2026-04-13 | 2 hypotheses Top: 0.484
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.57 · 2026-04-15
closed · Rounds: 4 · Score: 0.65 · 2026-04-13
Hypotheses and analyses mentioning O-GlcNAc in their description or question text
No additional research found