| Gene Symbol | OGT |
| Full Name | O-GlcNAc N-acetylglucosaminyltransferase |
| Aliases | Gene profile: OGT |
| Chromosome | Xq13.1 |
| Function | OGT catalyzes the transfer of a single GlcNAc from UDP-GlcNAc to the hydroxyl group of serine and threonine residues on target proteins |
| Primary Expression | neurons and glia: |
| Molecular Weight | ~110 kDa (nuclear isoform) |
| Amino Acids | 016 aa |
| Pathways | Apoptosis, Autophagy, Glycolysis, Immune Response, Inflammasome |
| UniProt ID | O15294 |
| GeneCards | OGT |
| Human Protein Atlas | OGT |
| Protein Product | OGT (O-GlcNAc Transferase) |
| EC Number | 2.4.1.255 |
| Alternative Names | OGT, O-linked N-acetylglucosamine transferase, HRMT1L2 (hexosamine-1,4-N-acetylglucosaminyl transferase) |
| Associated Diseases | depression, neurodegeneration |
| Known Drugs/Compounds | ROS |
| Interactions | SLC7A11, ULK1, RIPK3, RIPK1, APP, STX17 |
| KG Connections | 145 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |