Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PACAP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| antidepressant response | regulates | phenotype | 0.95 |
| ADCYAP1R1 | binds | gene | 0.95 |
| hippocampal dentate gyrus | expressed_in | brain_region | 0.90 |
| Cardiac Fibrosis | protects_against | disease | 0.90 |
| depression | protects_against | disease | 0.85 |
| depression-like behaviors | prevents | phenotype | 0.85 |
| Extracellular Matrix Deposition | inhibits | process | 0.85 |
| Sirtuin3 | interacts_with | protein | 0.80 |
| Alzheimer's disease | treats | disease | 0.80 |
| Chronic Inflammation | inhibits | process | 0.78 |
| Source | Relation | Type | Str |
|---|---|---|---|
| paroxetine | promotes | drug | 0.90 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||