PFOA

Understanding Entity Pages

This page aggregates everything SciDEX knows about PFOA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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graph TD
    PFOA["PFOA"] -->|"causes"| Developmental_Neurotoxicity["Developmental Neurotoxicity"]
    style Developmental_Neurotoxicity fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    PFOA["PFOA"] -->|"risk factor for"| Neurodegenerative_Diseases["Neurodegenerative Diseases"]
    style Neurodegenerative_Diseases fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    PFOA["PFOA"] -->|"associated"| Alzheimer_S_Disease["Alzheimer'S Disease"]
    style Alzheimer_S_Disease fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    PFOA["PFOA"] -->|"modulates"| Cortical_Neurons["Cortical Neurons"]
    style Cortical_Neurons fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    PFOA["PFOA"] -->|"modulates"| Calcium_Activity["Calcium Activity"]
    style Calcium_Activity fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    PFOA["PFOA"] -->|"regulates"| RNA_Translational_Efficiency["RNA Translational Efficiency"]
    style RNA_Translational_Efficiency fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
    PFOA["PFOA"] -->|"risk factor for"| ovarian_cancer["ovarian cancer"]
    style ovarian_cancer fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
    PDE2A["PDE2A"] -->|"binds"| PFOA["PFOA"]
    style PDE2A fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    style PFOA fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold