protein

PPM1H

Entity Detail โ€” Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PPM1H: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

7Connections
0Hypotheses
0Analyses
4Outgoing
3Incoming

Summary

Page for PPM1H Protein

View on Wiki โ†’

๐Ÿ”ฌ Protein Info
Gene SymbolPPM1H
FunctionPpm1H Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
Subcellular Localization| Cytoplasm ! Protein Family | Protein phosphatase 2C (PP2C) family </div> ## O
Molecular Weight52.3 kDa
GeneCardsPPM1H
Human Protein AtlasPPM1H
Associated DiseasesALS, Parkinson
InteractionsLRRK2
KG Connections7 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Wiki Pages (3)

Knowledge base pages for this entity

Mitochondria-Lysosome Contact Site Dysfunction in Parkinson's Disease

mechanism ยท 3314 words
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PPM1H Protein

protein ยท 613 words
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Proteins

index ยท 296 words
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Pathway Diagram

flowchart TD
    N0["PPM1H"]
    N1["LRRK2"]
    N1 -->|"associated with"| N0
    N2["LRRK1"]
    N2 -->|"co expressed with"| N0
    N0 -->|"inhibits"| N1
    N3["ALS"]
    N0 -->|"associated with"| N3
    N4["Parkinson"]
    N0 -->|"associated with"| N4
    N5["Proteins"]
    N0 -->|"associated with"| N5

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    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef drug fill:#1a2a2a,stroke:#26c6da,color:#e0e0e0
    classDef cell_type fill:#2a1a2a,stroke:#ab47bc,color:#e0e0e0
    classDef phenotype fill:#2a2a1a,stroke:#ffa726,color:#e0e0e0
    classDef process fill:#1a2a2a,stroke:#66bb6a,color:#e0e0e0
    classDef biological_process fill:#1a2a2a,stroke:#66bb6a,color:#e0e0e0
    classDef concept fill:#1a1a2a,stroke:#7986cb,color:#e0e0e0
    classDef entity fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26c6da,color:#e0e0e0
    classDef index fill:#1a1a2a,stroke:#7986cb,color:#e0e0e0
    class N0 protein
    class N1 gene
    class N2 gene
    class N3 disease
    class N4 disease
    class N5 protein

Outgoing (4)

TargetRelationTypeStr
LRRK2inhibitsprotein0.88
ALSassociated_withdisease0.60
Parkinsonassociated_withdisease0.60
Proteinsassociated_withprotein0.50

Incoming (3)

SourceRelationTypeStr
LRRK2associated_withgene0.50
LRRK1co_expressed_withgene0.50
LRRK2co_expressed_withgene0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found