Entity Detail โ Knowledge Graph Node
This page aggregates everything SciDEX knows about PPM1H: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | PPM1H |
| Function | Ppm1H Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes. |
| Subcellular Localization | | Cytoplasm ! Protein Family | Protein phosphatase 2C (PP2C) family </div> ## O |
| Molecular Weight | 52.3 kDa |
| GeneCards | PPM1H |
| Human Protein Atlas | PPM1H |
| Associated Diseases | ALS, Parkinson |
| Interactions | LRRK2 |
| KG Connections | 7 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["PPM1H"]
N1["LRRK2"]
N1 -->|"associated with"| N0
N2["LRRK1"]
N2 -->|"co expressed with"| N0
N0 -->|"inhibits"| N1
N3["ALS"]
N0 -->|"associated with"| N3
N4["Parkinson"]
N0 -->|"associated with"| N4
N5["Proteins"]
N0 -->|"associated with"| N5
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classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
classDef drug fill:#1a2a2a,stroke:#26c6da,color:#e0e0e0
classDef cell_type fill:#2a1a2a,stroke:#ab47bc,color:#e0e0e0
classDef phenotype fill:#2a2a1a,stroke:#ffa726,color:#e0e0e0
classDef process fill:#1a2a2a,stroke:#66bb6a,color:#e0e0e0
classDef biological_process fill:#1a2a2a,stroke:#66bb6a,color:#e0e0e0
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classDef therapeutic fill:#1a2a2a,stroke:#26c6da,color:#e0e0e0
classDef index fill:#1a1a2a,stroke:#7986cb,color:#e0e0e0
class N0 protein
class N1 gene
class N2 gene
class N3 disease
class N4 disease
class N5 proteinHypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||