protein

PTP1BPROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about PTP1BPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Experiments

Summary

Ptp1B (Protein Tyrosine Phosphatase 1B) is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	PTP1B
Full Name	ptp1b-protein
Chromosome	20q13.13
Protein Type	Protein
Primary Expression	Thalamus, Hypothalamus, thalamus
Subcellular Localization	the cytoplasmic face of the endoplasmic reticulum (ER), where it dephosphorylates key
Pathways	Oxidative Stress, oxidative stress response, MAPK signaling
UniProt ID	Search UniProt
GeneCards	PTP1B
Human Protein Atlas	PTP1B
Interactions	JNK1, AMPK, OXIDATIVE STRESS, ATP, GAIN, AND
KG Connections	48 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: PTP1BPROTEIN — AlphaFold SEARCH Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

ptp1b-protein

protein · 1345 words

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Pathway Diagram

graph TD
    PTP1BPROTEIN["PTP1BPROTEIN"]
    neurodegeneration["neurodegeneration"]
    PTP1BPROTEIN -->|"implicated_in"| neurodegeneration
    style PTP1BPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found