Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about PROPOFOL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | PROPOFOL |
Knowledge base pages for this entity
graph TD
PROPOFOL["PROPOFOL"]
PROPOFOL -->|"binds"| HCN1["HCN1"]
PROPOFOL -->|"modulates"| Sleep_Wake_Transition["Sleep-Wake Transition"]
PROPOFOL -->|"binds"| S5_S6_Transmembrane_Groove["S5-S6 Transmembrane Groove"]
PROPOFOL -->|"modulates"| Voltage_Dependent_Gating["Voltage-Dependent Gating"]
PROPOFOL -->|"inhibits"| Voltage_Sensor_Conformational_["Voltage-Sensor Conformational Changes"]
HCRTR1["HCRTR1"] -->|"interacts"| PROPOFOL| Target | Relation | Type | Str |
|---|---|---|---|
| HCN1 | inhibits | entity | 0.95 |
| HCN1 | binds_to | entity | 0.95 |
| VOLTAGE-DEPENDENT GATING | associated_with | entity | 0.90 |
| EPILEPSY | treats | entity | 0.85 |
| Source | Relation | Type | Str |
|---|---|---|---|
| HCRTR1 | interacts_with | gene | 0.75 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||