Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SCABP3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | SCABP3 |
| Key Genes/Proteins | AHA2, CBL7, AHA2 C-TERMINAL REGION I, PLASMA MEMBRANE H+-ATPASE, AND, JUN |
| Related Diseases | Alkali Tolerance, salt stress tolerance, ALS, Als |
graph TD
SCABP3["SCABP3"]
SCABP3 -->|"interacts"| AHA2["AHA2"]
SCABP3 -->|"modulates"| Plasma_Membrane_H__ATPase_Acti["Plasma Membrane H+-ATPase Activity"]
SCABP3 -->|"involved_in"| Alkali_Tolerance["Alkali Tolerance"]
SCABP3 -->|"binds"| AHA2_C_TERMINAL_REGION_I["AHA2 C-TERMINAL REGION I"]
SCABP3 -->|"binds"| Calcium["Calcium"]
SCABP3 -->|"modulates"| PLASMA_MEMBRANE_H__ATPASE["PLASMA MEMBRANE H+-ATPASE"]
SCABP3 -->|"activates"| ALS["ALS"]
SCABP3 -->|"activates"| Als["Als"]
Ca2_["Ca2+"] -->|"binds"| SCABP3
CBL7["CBL7"] -->|"activates"| SCABP3
CALCINEURIN["CALCINEURIN"] -->|"activates"| SCABP3
JUN["JUN"] -->|"activates"| SCABP3| Target | Relation | Type | Str |
|---|---|---|---|
| AHA2 | interacts_with | protein | 0.95 |
| Plasma Membrane H+-ATPase Activity | modulates | process | 0.95 |
| CBL7 | associated_with | gene | 0.95 |
| Alkali Tolerance | involved_in | phenotype | 0.90 |
| AHA2 C-TERMINAL REGION I | binds | protein | 0.90 |
| Calcium | binds | compound | 0.90 |
| Alkali Tolerance | associated_with | phenotype | 0.90 |
| PLASMA MEMBRANE H+-ATPASE | modulates | protein | 0.85 |
| salt stress tolerance | associated_with | phenotype | 0.80 |
| ALS | activates | disease | 0.65 |
| Als | activates | disease | 0.65 |
| AND | activates | gene | 0.60 |
| JUN | activates | gene | 0.60 |
| T Cell | activates | cell_type | 0.60 |
| CBL7 | activates | gene | 0.60 |
| CALCINEURIN | activates | gene | 0.60 |
| T Cell | expressed_in | cell_type | 0.55 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Ca2+ | binds | compound | 0.95 |
| CBL7 | activates | gene | 0.60 |
| CALCINEURIN | activates | gene | 0.60 |
| JUN | activates | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||