Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SLC9A7: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | SLC9A7 |
| Full Name | Solute Carrier Family 9 Member A7 |
| Chromosome | Xp11.23 |
| Function | is a member of the solute carrier family 9 (SLC9A) that encodes a sodium/hydrogen antiporter. |
| Subcellular Localization | SLC9A7 exhibits a distinctive subcellular localization pattern that distinguishes it from other NHE family members: |
| Amino Acids | 561 aa |
| UniProt ID | [Q9Y5P8](https://www.uniprot.org/uniprot/Q9Y5P8) |
| GeneCards | SLC9A7 |
| Human Protein Atlas | SLC9A7 |
| Associated Diseases | Als, Cancer, Carcinoma, Tumor |
| KG Connections | 7 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
SLC9A7["SLC9A7"]
Carcinoma{"Carcinoma"}
SLC9A7 -->|"associated with"| Carcinoma
Als{"Als"}
SLC9A7 -->|"associated with"| Als
Cancer{"Cancer"}
SLC9A7 -->|"associated with"| Cancer
Tumor{"Tumor"}
SLC9A7 -->|"associated with"| Tumor
neurodegeneration["neurodegeneration"]
SLC9A7 -->|"implicated in"| neurodegeneration
CD4["CD4"]
CD4 -->|"regulates"| SLC9A7
CD8["CD8"]
CD8 -->|"associated with"| SLC9A7
CANCER["CANCER"]
CANCER -->|"associated with"| SLC9A7
style SLC9A7 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning SLC9A7 in their description or question text
No additional research found