entity

T4

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about T4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

4Connections
1Hypotheses
0Analyses
2Outgoing
2Incoming

Wiki Pages (20)

Knowledge base pages for this entity

Personalized Treatment Plan — Atypical Parkinsonism (CBS/PSP)

therapeutic · 15794 words

williams-syndrome

disease · 5022 words

Circadian Rhythm in Neurodegeneration

mechanism · 4939 words

Lithium for PSP/CBS — Phase 2 Trial

clinical · 4474 words

GBA Pathway in Parkinson's Disease

mechanism · 4381 words

Outgoing (2)

TargetRelationTypeStr
Growthregulatesphenotype0.90
Nuclear Receptorsbindsreceptor0.85

Incoming (2)

SourceRelationTypeStr
SLCO1C1transportsgene0.90
MCT8binds_toprotein0.60

Targeting Hypotheses (1)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
Astrocyte MCT1/MCT4 Ratio Disruption with Metabolic Uncoupli 0.455 Alzheimer's Disease Cell type vulnerability in Alzheimers Di

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (20)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
Preventive Effects of Probiotic Formula on Metabolic Stress Associated Physical [PMID:41958144] Song JG, Bae HJ, Lee DH, Seo J, Lee B et J Microbiol Biotechnol 2026 0
Ion Channel-Extracellular Matrix Interplay in Colorectal Cancer: A Network-Based [PMID:40507957] Terzi A, Maqoud F, Guido D, Mallardi D, International journal of molec 2025 0
Direct mitochondrial import of lactate supports resilient carbohydrate oxidation [PMID:39416192] Cluntun AA, Visker JR, Velasco-Silva JN, bioRxiv : the preprint server 2024 0
Indole Derivatives as New Structural Class of Potent and Antiproliferative Inhib [PMID:36584238] Puri S, Stefan K, Khan SL, Pahnke J, Ste Journal of medicinal chemistry 2023 0
Transcriptomic cytoarchitecture reveals principles of human neocortex organizati [PMID:37824655] Jorstad NL, Close J, Johansen N, Yanny A Science (New York, N.Y.) 2023 0
[WALANT - Wide Awake Local Anaesthesia No Tourniquet: Complications in elective [PMID:35168268] Wieschollek S, Forster S, Megerle K Handchirurgie, Mikrochirurgie, 2022 0
SLC gene mutations and pediatric neurological disorders: diverse clinical phenot [PMID:34797406] Mir A, Almudhry M, Alghamdi F, Albaradie Human genetics 2022 0
Amyloid-β42 stimulated hippocampal lactate release is coupled to glutamate uptak [PMID:35177691] Hascup ER, Sime LN, Peck MR, Hascup KN Scientific reports 2022 0
Editor's Review and Introduction: Cognition-Inspired Artificial Intelligence. [PMID:35853452] Cassenti DN, Veksler VD, Ritter FE Topics in cognitive science 2022 0
Innovations in systemic sclerosis. [PMID:34483059] Johnson SR Best practice & research. Clin 2021 0
Macrophage monocarboxylate transporter 1 promotes peripheral nerve regeneration [PMID:34491913] Jha MK, Passero JV, Rawat A, Ament XH, Y The Journal of clinical invest 2021 0
Genome sequencing analysis identifies new loci associated with Lewy body dementi [PMID:33589841] Chia R, Sabir MS, Bandres-Ciga S, Saez-A Nature genetics 2021 0
Complete Genome Sequence of Geobacter sp. Strain FeAm09, a Moderately Acidophili [PMID:33446582] Yadav P, Antony-Babu S, Hayes E, Healy O Microbiology resource announce 2021 0
Engineering complex communities by directed evolution. [PMID:33986540] Chang CY, Vila JCC, Bender M, Li R, Mank Nature ecology & evolution 2021 0
Successful Nonoperative Treatment of Osteochondritis Dissecans of the Humeral Ca [PMID:34825100] Tajika T, Kuboi T, Endo F, Hatori Y, Sai Progress in rehabilitation med 2021 0
Neural crest-derived tumor neuroblastoma and melanoma share 1p13.2 as susceptibi [PMID:31605138] Avitabile M, Succoio M, Testori A, Cardi Carcinogenesis 2020 0
Manassantin B shows antiviral activity against coxsackievirus B3 infection by ac [PMID:31253850] Song JH, Ahn JH, Kim SR, Cho S, Hong EH, Scientific reports 2019 0
Brain Glucose Metabolism: Integration of Energetics with Function. [PMID:30565508] Dienel GA Physiological reviews 2019 0
A ketogenic drink improves brain energy and some measures of cognition in mild c [PMID:31027873] Fortier M, Castellano CA, Croteau E, Lan Alzheimer's & dementia : the j 2019 0
Epigenetic dysregulation in chronic myeloid leukaemia: A myriad of mechanisms an [PMID:28778403] Koschmieder S, Vetrie D Seminars in cancer biology 2018 0