protein

TAC1PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TAC1PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

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Summary

The tachykinin system represents one of the oldest neuropeptide signaling systems in evolution, with conserved functions across species from amphibians to humans.

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🔬 Protein Info

Gene Symbol	TAC1PROTEIN
Chromosome	7q21
Function	The tachykinin system represents one of the oldest neuropeptide signaling systems in evolution, with conserved functions across species from amphibians to humans.
Primary Expression	distinct neuronal populations within the basal ganglia, cortex, hippocampus, and brainstem, where they modulate dopaminergic signaling, GABAergic tran
Molecular Weight	17 kDa
Amino Acids	11 aa
GeneCards	TAC1PROTEIN
Human Protein Atlas	TAC1PROTEIN
Receptor	Primary Ligand
NK1R (TACR1)	Substance P
NK2R (TACR2)	Neurokinin A
NK3R (TACR3)	Neurokinin B
Compound	Indication
Aprepitant	AD
NK1 antagonist	PD
Associated Diseases	neurodegeneration
Interactions	TRPM8, WNT3A
KG Connections	27 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

TAC1 (Tachykinin Precursor 1) Protein

protein · 1709 words

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Pathway Diagram

graph TD
    TAC1PROTEIN["TAC1PROTEIN"]
    neurodegeneration["neurodegeneration"]
    TAC1PROTEIN -->|"implicated_in"| neurodegeneration
    style TAC1PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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No outgoing edges

Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity