gene

YARS2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about YARS2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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Summary

Comprehensive guide to YARS2 gene, a mitochondrial aminoacyl-tRNA synthetase involved in mitochondrial translation and neurodegenerative diseases

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🧬 Gene Info

Gene Symbol	YARS2
Full Name	Tyrosyl-tRNA Synthetase 2, Mitochondrial
Chromosome	12p11.21
Protein Type	Mitochondrial aminoacyl-tRNA synthetase
Function	encodes a mitochondrial aminoacyl-tRNA synthetase (mtaaRS) that catalyzes the attachment of tyrosine to its cognate mitochondrial tRNA during mitochondrial translation.
Subcellular Localization	or stability
Molecular Weight	52 kDa
Amino Acids	495 aa
Exons	13
UniProt ID	Q9Y2Z4
NCBI Gene ID	51091
Ensembl ID	ENSG00000143398
OMIM	613739
GeneCards	YARS2
Human Protein Atlas	YARS2
Associated Diseases	Alzheimer's disease, Parkinson's disease
Databases	GeneCards HPA STRING

🔮 Predicted Structure: YARS2 — AlphaFold Q9Y2Z4 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

YARS2 — Tyrosyl-tRNA Synthetase 2, Mitochondrial

gene · 1561 words

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Pathway Diagram

graph TD
    YARS2["YARS2"]
    neurodegeneration["neurodegeneration"]
    YARS2 -->|"implicated_in"| neurodegeneration
    style YARS2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning YARS2 in their description or question text

No additional research found