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clinical 3,822 words KG: genistein
Contents

Genistein for Mild Cognitive Impairment (NCT07385937)

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Related Hypotheses (20)

TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73Palmitoylation-Targeted BACE1 Trafficking Disruptors
Score: 0.69APOE-Dependent Autophagy Restoration
Score: 0.89Circadian Clock-Autophagy Synchronization
Score: 0.76Cell-Type Specific TREM2 Upregulation in DAM Microglia
Score: 0.76APOE-TREM2 Interaction Modulation
Score: 0.74Lysosomal Enzyme Trafficking Correction
Score: 0.71Lysosomal Calcium Channel Modulation Therapy
Score: 0.70Perforant Path Presynaptic Terminal Protection Strategy
Score: 0.70Lysosomal Positioning Dynamics Modulation
Score: 0.69TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.65TFEB-PGC1α Mitochondrial-Lysosomal Decoupling
Score: 0.62TREM2-Dependent Microglial Senescence Transition
Score: 0.62TREM2-mediated microglial tau clearance enhancement
Score: 0.62TREM2-Mediated Selective Aggregate Clearance Pathway
Score: 0.58Digital Twin-Guided Metabolic Reprogramming
Score: 0.55Temporal Decoupling via Circadian Clock Reset
Score: 0.54Lysosomal Membrane Repair Enhancement
Score: 0.54

Related Analyses (2)

Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archivedLipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed

Related Experiments (3)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40Neural Stem Cell Therapy for Alzheimer's Disease
clinical · proposed · Score: 0.40Mouse Cdk5, p35, and p39 mutations in neuronal migration
validation · proposed · Score: 0.80

See Also (3)

MMP9 Gene
gene · KG edge: interacts_withNRF2 Gene
gene · KG edge: activatesNRF2 Activator Therapy
idea · KG edge: activates

Knowledge Graph (2 edges)

genistein activates NRF2
genistein activates TFEB

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