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Clinical: Synaptic Loss in Multiple System Atrophy (NCT05121012)
clinical
1,804 words
KG: synaptic_loss
Contents
Synaptic Loss in Multiple System Atrophy (NCT05121012)
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Related Hypotheses (11)
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
Sleep Spindle-Synaptic Plasticity Enhancement
Score: 0.72
TREM2 Conformational Stabilizers for Synaptic Discrimination
Score: 0.69
Excitatory Neuron Vulnerability via SLC17A7 Downregulation
Score: 0.67
Synaptic Phosphatidylserine Masking via Annexin A1 Mimetics
Score: 0.62
Synaptic Vesicle Tau Capture Inhibition
Score: 0.58
Trans-Synaptic Adhesion Molecule Modulation
Score: 0.54
Glymphatic System-Enhanced Antibody Clearance Reversal
Score: 0.54
Blood-Brain Barrier SPM Shuttle System
Score: 0.53
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48
Related Analyses (13)
Blood-brain barrier transport mechanisms for antibody therap
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Tau propagation mechanisms and therapeutic interception poin
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Cell type vulnerability in Alzheimer's Disease (SEA-AD data
neurodegeneration · completed
Neuroinflammation resolution mechanisms and pro-resolving me
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What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
Synaptic pruning by microglia in early AD
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · completed
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Lipid raft composition changes in synaptic neurodegeneration
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Show 8 more
Related Experiments (1)
Cytochrome Therapeutics
clinical · proposed · Score: 0.40
Knowledge Graph (12 edges)
phagocytosis
causes
synaptic_loss
mechanisms-synaptic-loss-ad
describes
synaptic_loss
tripartite_synapse_dysfunction
causes
synaptic_loss
complement_cascade
causes
synaptic_loss
Alzheimer's_disease
causes
synaptic_loss
tripartite_synapse_dysfunction
NULL
synaptic_loss
synaptic_loss
associated_with
alzheimers
synaptic_loss
causes
Cognitive decline
synaptic_loss
associated_with
Cognitive decline
soluble_tau_oligomers
causes
synaptic_loss
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