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Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propagation

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Related Hypotheses (5)

Noradrenergic-Tau Propagation Blockade
Score: 0.71
Gut Barrier Permeability-α-Synuclein Axis Modulation
Score: 0.53
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.51
Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.48
Microbiome-Derived Tryptophan Metabolite Neuroprotection
Score: 0.43

Related Analyses (5)

What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · completed
Sleep disruption as cause and consequence of neurodegenerati
neurodegeneration · archived
GBA-Synuclein Loop Therapeutics for PD
neurodegeneration · completed
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

Related Experiments (3)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Gut Microbiome-Derived Metabolites in Alpha-Synuclein Propag
clinical · proposed · Score: 0.40
SCFA-Mediated Neuroinflammation in Alzheimer's Disease
clinical · proposed · Score: 0.40

Knowledge Graph (8 edges)

Gut Microbiome associated_with Parkinson'S Disease
Microbiota-Gut-Brain Axis mediates Parkinson's Disease Progression
Gut Microbiota Composition correlates_with Parkinson's Disease Development
Enteric Nervous System mediates Gut-to-Brain Alpha-Synuclein Spread
Brain mediates Gut
Brain-to-Gut Signal associated_with Intestinal Fat Absorption
Brain-to-Gut Signal targets Intestine
Gut Dysbiosis causes Gut-Brain Axis Dysfunction

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