Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about INDOLE-3-LACTIC ACID: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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graph TD
INDOLE_3_LACTIC_ACID["INDOLE-3-LACTIC ACID"]
INDOLE_3_LACTIC_ACID -->|"activates"| Aryl_Hydrocarbon_Receptor["Aryl Hydrocarbon Receptor"]
INDOLE_3_LACTIC_ACID -->|"activates"| Aryl_hydrocarbon_receptor["Aryl-hydrocarbon receptor"]
INDOLE_3_LACTIC_ACID -->|"activates"| AHR["AHR"]
INDOLE_3_LACTIC_ACID -->|"treats"| Amyloidopathy["Amyloidopathy"]
INDOLE_3_LACTIC_ACID -.prevents.-> depression["depression"]
INDOLE_3_LACTIC_ACID -->|"activates"| AhR_signaling["AhR signaling"]
INDOLE_3_LACTIC_ACID -->|"expressed in"| hippocampus["hippocampus"]
ALDH["ALDH"] -->|"encodes"| INDOLE_3_LACTIC_ACID
Bifidobacterium_breve["Bifidobacterium breve"] -->|"produces"| INDOLE_3_LACTIC_ACID| Target | Relation | Type | Str |
|---|---|---|---|
| Amyloidopathy | associated_with | disease | 0.95 |
| Aryl Hydrocarbon Receptor | activates | receptor | 0.95 |
| Aryl-hydrocarbon receptor | activates | receptor | 0.95 |
| Amyloidopathy | treats | disease | 0.85 |
| depression | prevents | disease | 0.85 |
| AhR signaling | activates | pathway | 0.85 |
| hippocampus | expressed_in | brain_region | 0.80 |
| Amyloidopathy | associated_with | disease | 0.80 |
| DEPRESSION | biomarker_for | disease | 0.80 |
| DEPRESSION | protects_against | disease | 0.80 |
| amyloidopathy | protects_against | process | 0.60 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Microbiome | associated_with | process | 0.95 |
| Microbiome | associated_with | process | 0.95 |
| ALDH | encodes | gene | 0.90 |
| Bifidobacterium breve | produces | organism | 0.90 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity