Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about labile iron pool: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Target | Relation | Type | Str |
|---|---|---|---|
| lipid peroxidation | causes | mechanism | 0.70 |
| ferroptosis | activates | mechanism | 0.70 |
| Fenton chemistry | causes | mechanism | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| H63D HFE | alters | gene | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| Labile iron pool expansion amplifies genotype-specific ALS f | 0.664 | neurodegeneration | Ferroptosis in ALS motor neuron vulnerab |
| Iron Chelation Therapy Targeting the Labile Iron Pool | 0.640 | neurodegeneration | Can ferroptosis inhibitors prevent BBB d |
Scientific analyses that reference this entity
neurodegeneration | 2026-04-25 | 12 hypotheses Top: 0.838
neurodegeneration | 2026-04-15 | 2 hypotheses Top: 0.586
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.73 · 2026-04-25
closed · Rounds: 4 · Score: 0.95 · 2026-04-15
Hypotheses and analyses mentioning labile iron pool in their description or question text
No additional research found