Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about LIPID RAFTS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | LIPID RAFTS |
graph TD
LIPID_RAFTS["LIPID RAFTS"]
LIPID_RAFTS -->|"modulates"| COMPLEMENT_REGULATORY_PROTEINS["COMPLEMENT-REGULATORY PROTEINS"]
LIPID_RAFTS -->|"supports"| TREM2["TREM2"]
LIPID_RAFTS -->|"activates"| MICROGLIA["MICROGLIA"]
LIPID_RAFTS -->|"activates"| NEURON["NEURON"]
LIPID_RAFTS -->|"inhibits"| NEUROINFLAMMATION["NEUROINFLAMMATION"]
Gangliosides["Gangliosides"] -->|"component_of"| LIPID_RAFTS
APP["APP"] -->|"regulates"| LIPID_RAFTS
INFLAMMATION["INFLAMMATION"] -->|"regulates"| LIPID_RAFTS
COMPLEMENT["COMPLEMENT"] -->|"regulates"| LIPID_RAFTS
HIPPOCAMPUS["HIPPOCAMPUS"] -->|"implicated in"| LIPID_RAFTS
AMYLOID["AMYLOID"] -->|"regulates"| LIPID_RAFTS
EXTRACELLULAR_VESICLES["EXTRACELLULAR VESICLES"] -->|"interacts"| LIPID_RAFTS
ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"] -.protects against.-> LIPID_RAFTS| Target | Relation | Type | Str |
|---|---|---|---|
| COMPLEMENT-REGULATORY PROTEINS | associated_with | protein | 0.85 |
| TREM2 | supports | protein | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Gangliosides | component_of | compound | 0.80 |
| AΒ | drives_formation_of | protein | 0.80 |
| AIBP | disrupts | gene | 0.80 |
| alpha-synuclein | associated_with | protein | 0.70 |
| neuronal ceramide synthesis | associated_with | phenotype | 0.70 |
| C1q | associated_with | protein | 0.70 |
| LRRK2 | associated_with | protein | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neuroinflammation | 2026-04-16 | 5 hypotheses Top: 0.597
neurodegeneration | 2026-04-15 | 1 hypotheses Top: 0.732
neurodegeneration | 2026-04-01 | 8 hypotheses Top: 0.525
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.94 · 2026-04-16
closed · Rounds: 4 · Score: 0.84 · 2026-04-16
closed · Rounds: 4 · Score: 0.90 · 2026-04-06
Hypotheses and analyses mentioning LIPID RAFTS in their description or question text
No additional research found