Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about perineuronal nets: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
No AI portrait yet
| Target | Relation | Type | Str |
|---|---|---|---|
| Neuronal Connections | associated_with | process | 0.90 |
| Plasticity | associated_with | process | 0.90 |
| critical_period_plasticity | associated_with | phenotype | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Childhood Abuse | causes | phenotype | 0.85 |
| Depression | associated_with | disease | 0.85 |
| HAPLN4 | component_of | gene | 0.80 |
| MMP2 | degrades | gene | 0.80 |
| MMP2/MMP9 | associated_with | gene | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
spatial memory | 2026-04-08 | 7 hypotheses Top: 0.455
neurodegeneration | 2026-04-01 | 15 hypotheses Top: 0.822
neurodegeneration | 2026-04-01 | 0 hypotheses
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
closed · Rounds: 4 · Score: 0.40 · 2026-04-27
closed · Rounds: 4 · Score: 0.95 · 2026-04-09
closed · Rounds: 4 · Score: 0.89 · 2026-04-06
closed · Rounds: 4 · Score: 0.92 · 2026-04-01
Hypotheses and analyses mentioning perineuronal nets in their description or question text
No additional research found