🧫

GWAS of plasma pTau217 in East Asian cohort

active
experiment Created: 2026-04-11T00:50:30 By: experiment_extractor Quality: 95% ✓ SciDEX ID: experiment-exp-5a6f4c79-3293-4bc0-98f5-1
🧫 Experiment Protocol Genetic Associationproposed
N = 1,972
Related Entities
DACT1, DAAM1, APOE
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-11T00:50:30.817922'}
p_valueNone
protocolIllumina Asian Screening Array genotyping, quality control with PLINK, removal of related individuals using KING, Hardy-Weinberg equilibrium testing, principal component analysis with PLINK2
effect_sizeNone
sample_size1,972
source_pmid41804841
extracted_at2026-04-10T17:50:30.814992
_schema_version1
experiment_typegenetic_association
success_criteriagenome-wide significance (p < 5×10^-8)
expected_outcomesIdentification of genetic loci associated with plasma pTau217 levels, particularly expecting APOE associations given its known role in AD
statistical_methodsgenome-wide association analysis, principal component analysis
📊 Evidence Profile Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
58
Outgoing
65
0 supporting 0 contradicting 0 neutral
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