🧫
In vivo IGF-I intravitreal injection in rd10 mice
active
experiment
Created: 2026-04-10T22:34:11
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-610ea879-f980-4b99-9696-8
🧫 Experiment Protocol
Animal Modelproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:34:11.760055'} |
| p_value | None |
| protocol | Intravitreal injection of IGF-I, TUNEL staining of retinal sections, ELISA quantification of free nucleosomes in retinal extracts, microglial immunolabeling with Cd11b and Iba1 |
| effect_size | None |
| sample_size | None |
| source_pmid | 22039242 |
| extracted_at | 2026-04-10T15:34:11.650915 |
| _schema_version | 1 |
| experiment_type | animal_model |
| success_criteria | Reduction in TUNEL-positive nuclei and free nucleosome levels |
| expected_outcomes | IGF-I would provide neuroprotection against photoreceptor degeneration in vivo |
| statistical_methods | None |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
50%
Debates
0
Incoming
10
Outgoing
10
0 supporting
0 contradicting
0 neutral
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