🧫

In vivo autophagy modulation in atherosclerotic mice

active
experiment Created: 2026-04-04T05:26:15 By: experiment_extractor Quality: 85% ✓ SciDEX ID: experiment-exp-be4e51ca-79ea-420d-a0cd-9
🧫 Experiment Protocol Animal Modelproposed
Related Entities
P2RY12
Metadata
_origin{'url': None, 'type': 'internal', 'tracked_at': '2026-04-04T05:26:15.855114'}
p_valueNone
protocolP2RY12 inhibitor and chloroquine co-treatment, autophagy marker analysis in vascular tissue, plaque analysis
effect_sizeNone
sample_sizeNone
source_pmid32160082
extracted_at2026-04-03T22:26:15.619136
_schema_version1
experiment_typeanimal_model
success_criteriaIncreased autophagy markers with P2RY12 inhibition that are reversed by chloroquine treatment
expected_outcomesP2RY12 inhibition would promote autophagy, which could be blocked by chloroquine
statistical_methodsNone
📊 Evidence Profile Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
26
Outgoing
29
0 supporting 0 contradicting 0 neutral
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