The abstract states that COVID-19 can modify clinical presentations of manifested neurological disorders but provides no mechanistic explanation. Understanding these mechanisms is crucial for managing neurological patients during viral infections and could reveal novel disease-modifying pathways. Gap type: unexplained_observation Source paper: COVID-19 and neurological disorders: are neurodegenerative or neuroimmunological diseases more vulnerable? (2021, Journal of neurology, PMID:32696341)
Landscape Summary: What mechanisms explain how COVID-19 infection modifies the clinical spectrum of existing neurological disorders? is a 0.8 priority gap in neuroinflammation. It has 0 linked hypotheses with average composite score 0.000. Status: open.
Colonna, Sevlever, et al. (TREM2 biology)
What mechanisms explain how COVID-19 infection modifies the clinical spectrum of existing neurological disorders? — INVOKE-2 (completed)
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