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Fig. 1: Up-regulation of ZFP64 in DOX-resistant TNBC tissues was positively associated w...

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Fig. 1: Up-regulation of ZFP64 in DOX-resistant TNBC tissues was positively associated w...
Fig. 1Figure 1
Up-regulation of ZFP64 in DOX-resistant TNBC tissues was positively associated with high histone lactylation level. ( A & B ) Pan-Kla level in DOX-resistant/sensitive TNBC tissues was evaluated by immunofluorescence staining. ( C ) The protein levels of pan-Kla and H3K18la in DOX-resistant/sensitive TNBC tissues were assessed by Western blotting. ( D ) RT-qPCR analysis of ZFP64 mRNA expression in DOX-resistant/sensitive TNBC tissues. ( E ) Pearson correlation test analyzed the correlation between ZFP64 and lactylation levels. ( F ) Western blotting determined ZFP64 protein abundance in DOX-resistant/sensitive TNBC tissues. ( G ) Co-localization of ZFP64 and H3K18la in DOX-resistant/sensitive TNBC tissues was observed by immunofluorescence staining. Student’s t test was performed for statistical analysis. * p  < 0.05, ** p  < 0.01, *** p  < 0.001
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Metadata
doi10.1186/s12967-025-06246-3
pmcidPMC11871786
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captionUp-regulation of ZFP64 in DOX-resistant TNBC tissues was positively associated with high histone lactylation level. ( A & B ) Pan-Kla level in DOX-resistant/sensitive TNBC tissues was evaluated by imm
paper_id707e4dfb-3896-4244-8e2a-7a749d45b168
image_urlhttps://www.ebi.ac.uk/europepmc/articles/PMC11871786/bin/12967_2025_6246_Fig1_HTML.jpg
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description
figure_labelFig. 1
figure_number1
_schema_version1
source_strategypmc_api
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