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Fig. 2 — A novel derivative of valepotriate inhibits the PI3K/AKT pathway and causes Noxa

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paper figure Created: 2026-04-21T18:29:40 By: paper_figures_tool Quality: 50% 🔗 External ID: paper-fig-paper-8281d7c4ac82-2
Fig. 2 — A novel derivative of valepotriate inhibits the PI3K/AKT pathway and causes Noxa
Fig. 2Figure 2
Amcp inhibited the proliferation of human pancreatic cancer cells. a The chemical structure of Amcp. b The time- and dose-dependent inhibitory effects of Amcp on two human pancreatic cancer cell lines, BxPC-3 and SW1990, in vitro. Cells were treated with Amcp at concentrations of 0.625, 1.25, 2.5, 5, and 10 µM for either 24, 48, or 72 h before the CCK-8 assay. c DAPI staining of the cell nucleus. Cells were treated with the indicated compounds for 24 h before fixation and stained with DAPI stain. Fluorescence was observed by using microscopy (Nikon Eclipse Ti). The magnification is ×400. Scale bar = 20 µm.
PubMed: paper-8281d7c4ac82
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pmidpaper-8281d7c4ac82
captionAmcp inhibited the proliferation of human pancreatic cancer cells. a The chemical structure of Amcp. b The time- and dose-dependent inhibitory effects of Amcp on two human pancreatic cancer cell li
image_urlhttps://www.ebi.ac.uk/europepmc/articles/PMC7470838/bin/41401_2019_354_Fig2_HTML.jpg
paper_titleA novel derivative of valepotriate inhibits the PI3K/AKT pathway and causes Noxa-dependent apoptosis in human pancreatic cancer cells.
figure_labelFig. 2
figure_number2
_schema_version1
source_strategypmc_api
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