| sess_457c5bc3-21d8-4 | What cell-type-specific gene regulatory networks mediate the DPP6 GWAS signal fo | 0.67 | 3 | 4 | completed | 2026-04-28 | 457c5bc3-21d8-42a3-bb99-b0fc6f3f9554 |
| sess_dfb32151-9c40-4 | What sex-specific microglial transcriptional states emerge in response to amyloi | 0.67 | 3 | 4 | completed | 2026-04-28 | dfb32151-9c40-452d-8063-0c57bae5c3d6 |
| sess_ana_f07c10cf-7e | Can targeting oxidative stress pathways (NRF2, SOD1, mitochondrial ROS) upstream | 0.62 | 0 | 6 | completed | 2026-04-27 | f07c10cf-7e5a-4a02-9479-327aa5c963b5 |
| sess_ana_26866808-a2 | How do GWAS-identified PD risk variants at the LRRK2 locus alter lysosomal membr | 0.89 | 0 | 6 | completed | 2026-04-27 | 26866808-a2cf-4e6e-976d-bc900aef6e0a |
| sess_ana_0847737b-b8 | What spatially resolved cell-cell communication networks between oligodendrocyte | 0.83 | 0 | 6 | completed | 2026-04-27 | 0847737b-b8f3-4130-b8c2-65015add1117 |
| ds-target-d9e2b8db2a | Should neuronal identity transcription factors be prioritized as therapeutic tar | 0.72 | 0 | 3 | completed | 2026-04-27 | |
| sess_ext_h-2600483e_ | Extended debate: CYP46A1 Overexpression Gene Therapy | 0.95 | 0 | 6 | completed | 2026-04-27 | SDA-2026-04-01-gap-lipid-rafts-2026-04-01 |
| sess_ext_SDA-2026-04 | Extended debate: Metabolic Reprogramming to Reverse Senescence | 0.95 | 0 | 6 | completed | 2026-04-27 | SDA-2026-04-04-gap-senescent-clearance-neuro |
| sess_ext_h-var-de167 | Extended debate: TREM2-Dependent Astrocyte-Microglia Cross-talk in Neurodegenera | 0.95 | 0 | 6 | completed | 2026-04-27 | SDA-2026-04-26-trem2-showcase |
| sess_ext_h-var-58e76 | Extended debate: Closed-loop transcranial focused ultrasound with 40Hz gamma ent | 0.95 | 0 | 6 | completed | 2026-04-27 | SDA-2026-04-03-26abc5e5f9f2 |
| sess_ext_h-var-3b982 | Extended debate: Closed-loop tACS targeting EC-II SST interneurons to block tau | 0.95 | 0 | 6 | completed | 2026-04-27 | SDA-2026-04-03-26abc5e5f9f2 |
| pan_e0f8efc0 | are LLMs conscious? | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| pan_f11f02fc | Is the amyloid cascade hypothesis still the best explanation for AD? | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| test-chamber-session | test question | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| pan_f3022c8f | Is the amyloid cascade hypothesis still the best explanation for AD? | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| test-chamber-session | test question | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| test-debate-1ba85200 | Does APOE4 drive tau propagation via mitochondrial dysfunction? | 0.75 | 0 | 0 | completed | 2026-04-27 | |
| test-debate-7bf87108 | Does APOE4 drive tau propagation via mitochondrial dysfunction? | 0.75 | 0 | 0 | completed | 2026-04-27 | |
| pan_46017aa0 | smoke - what is the strongest evidence against the amyloid cascade | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| pan_01105bdc | what is the root cause of alzheimer's | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| pan_41ec088e | smoke - what is the strongest evidence against the amyloid cascade | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| pan_b2789997 | smoke - what is the strongest evidence against the amyloid cascade | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| pan_af7f06b2 | smoke | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| pan_853885a7 | smoke - what is the strongest evidence against the amyloid cascade hypothesis | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| sess_hyp_h-3b539acf_ | Neutrophil Extracellular Trap (NET) Inhibition: ## Mechanistic Overview
Neutroph | 0.80 | 0 | 4 | completed | 2026-04-27 | |
| pan_cc6c3500 | smoke test - what is dopamine | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| pan_b6c942aa | what is the root cause of alzheimer's | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| sess-hyp-ec7c58c65ca | Debate: Closed-loop transcranial focused ultrasound targeting entorhinal PV inte | 0.65 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-03-26abc5e5f9f2 |
| sess-hyp-ac3663c415c | Debate: Chromatin Remodeling-Mediated Nutrient Sensing Restoration | 0.46 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-04-gap-epigenetic-reprog-b685190e |
| sess-hyp-3a782e02e23 | Debate: TREM2 R47H Metabolic Lock-in at Cholesterol Ester Accumulation | 0.59 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-15-gap-debate-20260410-112522-57d1cc4f |
| sess-hyp-81fef13b19a | Debate: Interneuron SYNGAP1 Deficiency Disrupts Cortical Circuit Assembly During | 0.71 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-15-gap-pubmed-20260411-084510-fbfafe2c |
| sess-hyp-87b85c3b19f | Debate: Closed-loop tACS targeting EC-II SST interneurons to block tau propagati | 0.71 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-03-26abc5e5f9f2 |
| sess-hyp-8a90163989d | Debate: Closed-loop transcranial focused ultrasound to restore hippocampal gamma | 0.87 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-03-26abc5e5f9f2 |
| sess-hyp-a599791d436 | Debate: Closed-loop tACS targeting EC-II PV interneurons to suppress burst firin | 0.48 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-03-26abc5e5f9f2 |
| sess-hyp-f093318d54c | Debate: Liquid-to-Solid Transition Pathology Reveals Granule Weak Points | 0.58 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-07-gap-pubmed-20260406-041428-53b81741 |
| sess-hyp-10e827fe5d5 | Debate: LPCAT3-Mediated Lands Cycle Remodeling as the Primary Ferroptotic Primin | 0.12 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-03-gap-seaad-v4-20260402065846 |
| sess-hyp-822bfd0cb89 | Debate: ALOX15-Driven Enzymatic Ferroptosis in AD Oligodendrocytes via PUFA-PE P | 0.42 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-03-gap-seaad-v4-20260402065846 |
| sess-hyp-ecde86af7db | Debate: LPCAT3-Mediated Lands Cycle Amplification of Ferroptotic Vulnerability i | 0.48 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-03-gap-seaad-v4-20260402065846 |
| sess-hyp-af5c7b00499 | Debate: Enhancing Microglial Phagocytosis of Extracellular Tau via TREM2 Activat | 0.34 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-04-gap-tau-prion-spreading |
| pan_e387991a | what role does microglial TREM2 play in Alzheimer disease pathology | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| pan_81d65a6d | what role does microglial TREM2 play in Alzheimer disease pathology | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| sess-hyp-1b87d283fc0 | Debate: TREM2 Microglial Activation Rescues Amyloid Clearance in AD | 0.75 | 0 | 4 | completed | 2026-04-27 | test-hypothesis-fixtures-v1 |
| sess-hyp-9e94c8fee48 | Debate: TBK1 Loss Locks Microglia in an Aged/Senescent Transcriptional State, Fu | 0.33 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-26-gap-20260425215446 |
| sess-hyp-2d2eb00ec3a | Debate: TREM2 Deficiency Drives Microglial Senescence via Lipid Metabolism Dysre | 0.46 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-06-gap-pubmed-20260406-041439-5f43216e |
| sess-hyp-9935d8a1fc1 | Debate: Closed-loop tACS targeting EC-II somatostatin interneurons to restore de | 0.54 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-03-26abc5e5f9f2 |
| sess-hyp-78891e7dfa8 | Debate: ACSL4-Driven Ferroptotic Priming in Disease-Associated Oligodendrocytes | 0.47 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-03-gap-seaad-v4-20260402065846 |
| pan_efca73be | test convene from monitor | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| sess-hyp-0bb6b3633d4 | Debate: Microglial TREM2 downregulation impairs damage-associated response in la | 0.21 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-04-analysis_sea_ad_001 |
| pan_d51d054a | what is the root cause of alzheimer's | 0.50 | 0 | 0 | completed | 2026-04-27 | |
| sess-hyp-85e15db6a83 | Debate: Closed-loop transcranial focused ultrasound with real-time gamma feedbac | 0.19 | 0 | 4 | completed | 2026-04-27 | SDA-2026-04-03-26abc5e5f9f2 |