| target_debate_target | Should LOX (Lysyl oxidase) be prioritized as a therapeutic target for neurodegen | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| sess_SDA-2026-04-07- | The debate identified temporal specificity as a critical weakness - when exactly | 0.68 | 7 | 4 | completed | 2026-04-21 | SDA-2026-04-07-gap-debate-20260406-062039-7ef9980b |
| target_debate_target | Should P2RY12 (P2Y purinoreceptor 12) be prioritized as a therapeutic target for | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should HCRTR2 (Hypocretin Receptor 2) be prioritized as a therapeutic target for | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| sess_SDA-2026-04-07- | While the study establishes TDP-43 triggers mtDNA release via mPTP to activate c | 0.73 | 7 | 4 | completed | 2026-04-21 | SDA-2026-04-07-gap-pubmed-20260406-062141-611cf046 |
| target_debate_target | Should FCGRT (Fc fragment of IgG receptor and transporter) be prioritized as a t | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should HCRTR1 (Hypocretin Receptor 1) be prioritized as a therapeutic target for | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| sess_SDA-2026-04-07- | The abstract identifies APOE4 association with increased TDP-43 pathology but th | 0.61 | 7 | 4 | completed | 2026-04-21 | SDA-2026-04-07-gap-pubmed-20260406-062202-c8c5a9a1 |
| target_debate_target | Should SNCA (Synuclein alpha) be prioritized as a therapeutic target for neurode | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| sess_SDA-2026-04-07- | While the study identifies G3BP1 as a central node triggering phase separation, | 0.76 | 7 | 4 | completed | 2026-04-21 | SDA-2026-04-07-gap-pubmed-20260406-041428-53b81741 |
| target_debate_target | Should ULK1 (Unc-51 like autophagy activating kinase 1) be prioritized as a ther | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should ADRA2A (Alpha-2A adrenergic receptor) be prioritized as a therapeutic tar | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should HSPA1A (Heat Shock Protein Family A Member 1A) be prioritized as a therap | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should SLC7A11 (Cystine/glutamate transporter) be prioritized as a therapeutic t | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should ADORA2A (Adenosine A2A receptor) be prioritized as a therapeutic target f | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should APOE (Apolipoprotein E) be prioritized as a therapeutic target for neurod | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should CGAS (Cyclic GMP-AMP synthase) be prioritized as a therapeutic target for | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should TREM2 (Triggering receptor expressed on myeloid cells 2) be prioritized a | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should PDGFRB (Platelet-derived growth factor receptor beta) be prioritized as a | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should HSP90AA1 (Heat Shock Protein 90 Alpha Family Class A Member 1) be priorit | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should GLP1R (Glucagon-like peptide-1 receptor) be prioritized as a therapeutic | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should G3BP1 (Ras GTPase-activating protein-binding protein 1) be prioritized as | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should NLRP3 (NACHT, LRR and PYD domains-containing protein 3) be prioritized as | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| sess_SDA-2026-04-07- | The study shows P2RY12 regulates VSMC foam cell formation but doesn't explain wh | 0.66 | 7 | 4 | completed | 2026-04-21 | SDA-2026-04-07-gap-pubmed-20260406-041434-a4d6154a |
| target_debate_target | Should MTNR1B (Melatonin receptor 1B) be prioritized as a therapeutic target for | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| sess_SDA-2026-04-07- | The abstract describes IBA1 low/negative microglia in individuals with liver dis | 0.76 | 7 | 4 | completed | 2026-04-21 | SDA-2026-04-07-gap-pubmed-20260406-041439-306c2cdb |
| target_debate_target | Should P2RY1 (P2Y purinoreceptor 1) be prioritized as a therapeutic target for n | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| sess_SDA-2026-04-07- | The abstract states that AQP4 'is part of the pathogenesis' of CNS disorders and | 0.76 | 7 | 4 | completed | 2026-04-21 | SDA-2026-04-07-gap-pubmed-20260406-041445-ce0abc1e |
| target_debate_target | Should IL1B (Interleukin-1 beta) be prioritized as a therapeutic target for neur | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| sess_SDA-2026-04-07- | The debate raised this developmental hypothesis but couldn't resolve the mechani | 0.71 | 7 | 4 | completed | 2026-04-21 | SDA-2026-04-07-gap-debate-20260406-062045-56983337 |
| target_debate_target | Should TH (Tyrosine hydroxylase) be prioritized as a therapeutic target for neur | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| sess_SDA-2026-04-07- | The debate considered multiple propagation routes (synaptic, extracellular vesic | 0.66 | 6 | 4 | completed | 2026-04-21 | SDA-2026-04-07-gap-debate-20260406-062052-946439a8 |
| target_debate_target | Should PARP1 (Poly [ADP-ribose] polymerase 1) be prioritized as a therapeutic ta | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should C3 (Complement C3) be prioritized as a therapeutic target for neurodegene | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| sess_SDA-2026-04-07- | The sequential therapy hypothesis depends on identifying when autophagy failure | 0.78 | 7 | 4 | completed | 2026-04-21 | SDA-2026-04-07-gap-debate-20260406-062101-724971bc |
| target_debate_target | Should KCNK2 (Potassium two pore domain channel subfamily K member 2) be priorit | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| sess_SDA-2026-04-07- | While the study establishes C1QA and C1QC as diagnostic biomarkers and confirms | 0.71 | 7 | 4 | completed | 2026-04-21 | SDA-2026-04-07-gap-pubmed-20260406-062122-b65f8ebc |
| target_debate_target | Should PRKAA1 (AMP-activated protein kinase catalytic subunit alpha-1) be priori | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should RAB7A (Ras-related protein Rab-7a) be prioritized as a therapeutic target | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| sess_SDA-2026-04-07- | The study shows C1qa tags synapses for microglial elimination, but doesn't expla | 0.75 | 7 | 4 | completed | 2026-04-21 | SDA-2026-04-07-gap-pubmed-20260406-062128-c84a87d9 |
| target_debate_target | Should MTNR1A (Melatonin receptor 1A) be prioritized as a therapeutic target for | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should BCL2L1 (BCL2 Like 1) be prioritized as a therapeutic target for neurodege | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| sess_SDA-2026-04-07- | The abstract mentions multiple organelles synchronously present structural deran | 0.80 | 7 | 4 | completed | 2026-04-21 | SDA-2026-04-07-gap-pubmed-20260406-062132-e71b3ef7 |
| target_debate_target | Should P2RX7 (P2X purinoreceptor 7) be prioritized as a therapeutic target for n | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| sess_SDA-2026-04-07- | The study identifies cGAS/STING activation as a consequence of TDP-43-mediated m | 0.73 | 6 | 4 | completed | 2026-04-21 | SDA-2026-04-07-gap-pubmed-20260406-062141-fc60e018 |
| target_debate_target | Should IDH2 (Isocitrate Dehydrogenase 2) be prioritized as a therapeutic target | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should DRD2 (Dopamine receptor D2) be prioritized as a therapeutic target for ne | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should CACNA1G (Voltage-dependent T-type calcium channel subunit alpha-1G) be pr | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should LDLR (Low density lipoprotein receptor) be prioritized as a therapeutic t | 0.50 | 0 | 4 | completed | 2026-04-21 | |
| target_debate_target | Should GABRA1 (Gamma-aminobutyric acid receptor subunit alpha-1) be prioritized | 0.50 | 0 | 4 | completed | 2026-04-21 | |