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Clinical: Inclisiran for Lewy Body Disorders Trial
clinical
2,532 words
KG: inclisiran
2026-03-22
kind:clinical-trial
section:clinical-trials
state:published
disease:lewy-body-dementia
drug:inclisiran
target:pcsk9
technology:sirna
Contents
Inclisiran for Lewy Body Disorders Trial
Knowledge Graph
Related Hypotheses (18)
Membrane Cholesterol Gradient Modulators
Score: 0.52
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51
APOE4-Specific Microglial Metabolic Rescue
Score: 0.50
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59
Competitive APOE4 Domain Stabilization Peptides
Score: 0.56
APOE4 Allosteric Rescue via Small Molecule Chaperones
Score: 0.54
Targeted APOE4-to-APOE3 Base Editing Therapy
Score: 0.53
Lysosomal Calcium Channel Modulation Therapy
Score: 0.49
APOE4-Selective Lipid Nanoemulsion Therapy
Score: 0.49
APOE Isoform Expression Across Glial Subtypes
Score: 0.48
Interfacial Lipid Mimetics to Disrupt Domain Interaction
Score: 0.46
Lysosomal Membrane Repair Enhancement
Score: 0.45
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.45
Excitatory Neuron Vulnerability via SLC17A7 Downregulation
Score: 0.44
APOE Isoform Conversion Therapy
Score: 0.44
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Piezoelectric Nanochannel BBB Disruption
Score: 0.41
Trans-Synaptic Adhesion Molecule Modulation
Score: 0.34
Show 13 more
Related Analyses (4)
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Is disrupted sleep a cause or consequence of neurodegenerati
neurodegeneration · failed
Is disrupted sleep a cause or consequence of neurodegenerati
neurodegeneration · failed
Related Experiments (4)
ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
AD Amyloid-Resilient Phenotype Study — Why Some amyloid-Posi
clinical · proposed · Score: 0.40
AD Combination Therapy Trial: Anti-Aβ + Anti-Tau
clinical · proposed · Score: 0.40
Sex Differences in Alzheimer's Disease — mechanisms and ther
clinical · proposed · Score: 0.40
Knowledge Graph (1 edges)
inclisiran
inhibits
PCSK9