| Age | Primary risk factor, with incidence increasing substantially after age 65 |
| Genetics | Family history increases risk; specific risk alleles include: |
| Prodromal conditions | REM sleep behavior disorder (RBD) is a strong prodromal marker |
| Vascular risk factors | May contribute to disease onset and severity |
| Databases | OMIMOrphanetClinicalTrialsPubMed |