gene 1,933 words KG: ACVR1B 2026-03-25
kind:genesection:genesstate:publishedpriority:high
Contents

Activin A Receptor Type 1B (ACVR1B)

🧬 Gene Info
Gene SymbolACVR1B
Protein TypeSerine/Threonine Kinase
Functionis a type I serine/threonine kinase receptor that plays a critical role in TGF-β/activin signaling pathways.
Primary Expressionthe central nervous system and has been increasingly recognized for its involvement in neurodegenerative disease pathogenesis
GeneCardsACVR1B
Human Protein AtlasACVR1B
RegionExpression Level
Cerebral CortexHigh
HippocampusHigh
Basal GangliaModerate
CerebellumModerate
Substantia NigraModerate
Spinal CordVariable
SMAD2/3Phosphorylation
SMAD4Complex formation
Associated Diseasesneurodegeneration
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph