gene 4,687 words KG: APOC4
Contents

APOC4 — Apolipoprotein C-IV

🧬 Gene Info
Gene SymbolAPOC4
Full NameApolipoprotein C-IV
Chromosome19q13.32
Functionis a small (≈17 kDa) exchangeable apolipoprotein that can transfer between different lipoprotein particles.
Primary Expressionthe liver and, to a lesser extent, in the brain, where it participates in triglyceride-rich lipoprotein metabolism and may influence neurodegenerative
Molecular Weight17 kDa
Amino Acids146 aa
Exons4
UniProt IDP55056
NCBI Gene ID345
Ensembl IDENSG00000224259
OMIM607789
GeneCardsAPOC4
Human Protein AtlasAPOC4
Associated Diseasesneurodegeneration
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (31)

Ganglioside Rebalancing Therapy
Score: 0.69
Lysosomal Positioning Dynamics Modulation
Score: 0.69
Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.68
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
GAP43-mediated tunneling nanotube stabilization enhances neu
Score: 0.67
Mitochondrial RNA Granule Rescue Pathway
Score: 0.66
Oligodendrocyte White Matter Vulnerability
Score: 0.65
Mitochondrial SPM Synthesis Platform Engineering
Score: 0.65
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.62
CX43 hemichannel engineering enables size-selective mitochon
Score: 0.57
Piezoelectric Nanochannel BBB Disruption
Score: 0.52
← Prevpg 2/2

Related Analyses (2)

Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
APOE4 (Apolipoprotein E4)
disease · Pages share 4 hypotheses
LX1001 Phase 1/2 Trial (NCT03634007) - Gene Therapy for
clinical · Pages share 4 hypotheses
BEACoN Study - Biomarker Exploration in Aging, Cognitio
clinical · Pages share 4 hypotheses
Metabolomic Biomarkers in Neurodegeneration
biomarker · Pages share 3 hypotheses

Knowledge Graph (2 edges)

APOC4 data_in benchmark_ot_ad_answer_key:APOC4
benchmark_ot_ad_answer_key:APOC4 data_in APOC4

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