| Gene Symbol | ARF5 |
| Full Name | ADP Ribosylation Factor 5 |
| Chromosome | 7q31.2 |
| Protein Family | ARF GTPase family |
| Function | is a member of the ARF family of small GTPases that play critical roles in intracellular membrane trafficking[@casler2024arftraffic]. |
| Molecular Weight | 20 kDa |
| UniProt ID | [P26447](https://www.uniprot.org/uniprot/P26447) |
| Ensembl ID | ENSG00000104081 |
| OMIM | 103185 |
| GeneCards | ARF5 |
| Human Protein Atlas | ARF5 |
| N-terminal region | Contains a myristoylation site that facilitates membrane association |
| GTP-binding domain (G-domain) | Responsible for nucleotide binding and hydrolysis |
| Switch I and Switch II regions | Conformational changes upon GTP/GDP binding that mediate interactions with effectors |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsNCBI GeneHPASTRING |
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