gene 1,497 words KG: CASP5 2026-03-26
kind:genesection:genestopic:alzheimerstopic:parkinsons
Contents

CASP5 Gene

🧬 Gene Info
Gene SymbolCASP5
Full NameCaspase 5
Chromosome11q22.2
Protein FamilyCysteine-aspartic acid proteases
Functionis a key component of the non-canonical inflammasome pathway, which is distinct from the canonical caspase-1-dependent inflammasome.
UniProt IDQ9U2L0
NCBI Gene ID838
Ensembl IDENSG00000137757
OMIM602665
GeneCardsCASP5
Human Protein AtlasCASP5
Encoded ProteinCaspase-5
Associated DiseasesAlzheimer's disease, Parkinson's disease
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (6)

Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Circadian-Synchronized LRP1 Pathway Activation
Score: 0.53
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.51
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (15)

Neurodegeneration
disease · KG edge: implicated_in
Wnt/β-Catenin Signaling Pathway in Neurodegeneration
mechanism · Pages share 3 hypotheses
WNK1-Bilirubin Signaling in Neuroinflammation and Neuro
mechanism · Pages share 3 hypotheses
vip-vasoactive-intestinal-peptide-signaling-neurodegene
mechanism · Pages share 3 hypotheses
VEGF Signaling and Cerebral Angiogenesis in Neurodegene
mechanism · Pages share 3 hypotheses