| Gene Symbol | CHCHD3 |
| Full Name | Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 3 |
| Function | CHCHD3 encodes a mitochondrial protein containing twin coiled-coil helix (CHCH) domains. |
| Subcellular Localization | the **mitochondrial intermembrane space** where it forms homooligomers and heterooligomers with other CHCHD proteins |
| Amino Acids | 450 aa |
| UniProt ID | CHCHD3 |
| Ensembl ID | ENSG00000165237 |
| GeneCards | CHCHD3 |
| Human Protein Atlas | CHCHD3 |
| Mitochondrial cristae structure | Essential for maintaining mitochondrial cristae morphology |
| Respiratory chain function | Supports complex I and IV activity |
| Mitochondrial DNA maintenance | Protects mitochondrial genome integrity |
| Cell survival | Prevents apoptosis through mitochondrial pathways |
| Associated Diseases | neurodegeneration |
| Interactions | RB1CC1 |
| KG Connections | 2 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |