| Gene Symbol | GUCY1B1 |
| Full Name | Guanylate Cyclase 1 Soluble Subunit Beta 1 |
| Aliases | GUCY1B1, sGC-β1, GUCY1B, β1-sGC |
| Chromosome | 4q31.3 |
| Protein Family | Soluble guanylate cyclase subunits (GUCY1A1, GUCY1B1) |
| Protein Type | Enzyme - Guanylate cyclase |
| Function | The α₁β₁ sGC heterodimer performs multiple essential functions |
| Primary Expression | Both cytosolic and membrane-associated fractions, with the heterodimer distributed throughout the cytoplasm and in proximity to the plasma membrane |
| Subcellular Localization | Both cytosolic and membrane-associated fractions, with the heterodimer distributed throughout the cytoplasm and in proxi |
| Amino Acids | 619 aa |
| Pathways | Amyloid |
| UniProt ID | P21452 |
| NCBI Gene ID | 2983 |
| Ensembl ID | ENSG00000147862 |
| OMIM | 139397 |
| GeneCards | GUCY1B1 |
| Human Protein Atlas | GUCY1B1 |
| Associated Diseases | neurodegeneration |
| KG Connections | 29 knowledge graph edges |
| Databases | GeneCardsHPASTRING |