gene 1,325 words KG: RBFOX2 2026-03-24
kind:genesection:genesstate:published
Contents

RNA Binding Fox-1 Homolog 2 (RBFOX2)

🧬 Gene Info
Gene SymbolRBFOX2
Full NameRNA Binding Fox-1 Homolog 2 (RBFOX2)
Chromosome22q12.3
Protein TypeGene
FunctionIt plays critical roles in
Molecular Weight44.5 kDa
Amino Acids90 aa
PathwaysAmyloid
UniProt IDQ9BQY4
NCBI Gene ID61643
Ensembl IDENSG00000100320
GeneCardsRBFOX2
Human Protein AtlasRBFOX2
Associated DiseasesAmyotrophic Lateral Sclerosis (ALS), Parkinson's Disease, Cancer, Epilepsy, Autism Spectrum Disorder
InteractionsHNRNPM, CANCER
KG Connections34 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (11)

Circadian Clock-Autophagy Synchronization
Score: 0.55
Temporal Decoupling via Circadian Clock Reset
Score: 0.52
Cryptic Exon Silencing Restoration
Score: 0.46
Cross-Seeding Prevention Strategy
Score: 0.45
Glycine-Rich Domain Competitive Inhibition
Score: 0.43

Related Analyses (13)

RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
What determines the specificity of RNA-protein interactions
neurodegeneration · failed
How do dilncRNAs specifically drive molecular crowding and p
neurodegeneration · completed
What determines the specificity of DDR protein recruitment t
neurodegeneration · completed
Do chronic stress granule inhibition strategies impair norma
neurodegeneration · failed

Related Experiments (30)

Myricanol treatment in HFD-induced hyperlipidemic C57BL/6J m
validation · proposed · Score: 0.95
Single-cell RNA-seq analysis of mouse testes with gonadal de
exploratory · proposed · Score: 0.95
Sevoflurane-induced neurotoxicity (SIN) rat model
validation · proposed · Score: 0.95
FLS Stimulation and Transcriptomic Analysis
exploratory · proposed · Score: 0.95
Factor depletion effects on DDR focus formation in vivo
exploratory · proposed · Score: 0.90

See Also (10)

Tau Protein
protein · KG edge: regulates
Alzheimer Indonesia
institution · KG edge: regulates
RAC1 Gene
gene · KG edge: expressed_in
NFKBIA Gene (NFKB Inhibitor Alpha)
gene · KG edge: co_discussed
MYC Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

RBFOX2 expressed_in RAC1
RBFOX2 regulates MYC
RBFOX2 interacts_with HNRNPM
RBFOX2 regulates TAU
RBFOX2 expressed_in MEF2C
RBFOX2 expressed_in GUCY1B1
RBFOX2 regulates Nfkb
RBFOX2 expressed_in Rb
RBFOX2 interacts_with CANCER
RBFOX2 interacts_with Cancer